Burst-suppression is reactive to photic stimulation in comatose children with acquired brain injury.
نویسندگان
چکیده
OBJECTIVE Burst-suppression is an electroencephalographic pattern observed during coma. In individuals without known brain pathologies undergoing deep general anesthesia, somatosensory stimulation transiently increases the occurrence of bursts. We investigated the reactivity of burst-suppression in children with acquired brain injury. METHODS Intensive care unit electroencephalographic monitoring recordings containing burst-suppression were obtained from 5 comatose children with acquired brain injury of various etiologies. Intermittent photic stimulation was performed at 1Hz for 1min to assess reactivity. We quantified reactivity by measuring the change in the burst ratio (fraction of time in burst) following photic stimulation. RESULTS Photic stimulation evoked bursts in all patients, resulting in a transient increase in the burst ratio, while the mean heart rate remained unchanged. The regression slope of the change in burst ratio, referred to as the standardized burst ratio reactivity, correlated with subjects' Glasgow Coma Scale scores. CONCLUSIONS Reactivity of the burst-suppression pattern to photic stimulation occurs across diverse coma etiologies. Standardized burst ratio reactivity appears to reflect coma severity. SIGNIFICANCE Measurement of burst ratio reactivity could represent a simple method to monitor coma severity in critically ill children.
منابع مشابه
Effect of auditory and tactile stimulation by family members on the level of consciousness in comatose patients: A quasi-experimental study
Background & Aim: Decreased level of consciousness is one of the life-threatening complications associated with brain injuries. The aim of the study was to explore the effect of auditory and tactile stimulation by a family member on patients’ consciousness level. Methods & Materials: This quasi-experimental study was conducted on 80 comatose patients with traumatic brain injury hospitalized in...
متن کاملEffect of Auditory Stimulation with Occupational Noise on the Consciousness Level of Comatose Patients with Traumatic Brain Injury: A Clinical Trial Study
متن کامل
Effects of Organized Auditory Stimulation by Familiar Voice on Blood Pressure and Body Temperature in Comatose Patients
Introduction: Brain injury induced coma is the main cause of hospitalization of patients in the intensive care unit (ICU) and their consequent stressful physiological complications, which can be prevented using sensory stimulation as a therapeutic method. Nevertheless, identifying and using the optimal sensory stimulation program is crucial. Objective: The present study was conducted to de...
متن کاملEffect of Auditory Stimulation by Recitation of Prayers (Azan) on Consciousness Level of Comatose Patients: a Clinical Trial
Background and Objectives: Traumatic brain injury and resulted coma are major causes of death and disability. Coma stimulation techniques are recently proposed to improve coma status. The aim of this study was to assess the effect of hearing Azan on level of consciousness among patients. Materials and Methods: In this clinical trial, 33 patients with coma were randomly divided into two interven...
متن کاملContinuous noninvasive monitoring of barbiturate coma in critically ill children using the Bispectral™ index monitor
INTRODUCTION Traumatic brain injury and generalized convulsive status epilepticus (GCSE) are conditions that require aggressive management. Barbiturates are used to lower intracranial pressure or to stop epileptiform activity, with the aim being to improve neurological outcome. Dosing of barbiturates is usually guided by the extent of induced burst-suppression pattern on the electroencephalogra...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
دوره 127 8 شماره
صفحات -
تاریخ انتشار 2016